H PV P L E
  (n = 10) (n = 8) (n = 8) (n = 8) (n = 8)
Gly 65-70.2 58.5-61.9 50.7-54.1 44.3-48.8 37.9-41.8
  67.8 (1.78) 59.8 (1.29) 52.4 (1.16) 46.7 (1.45) 40 (1.27)
Ala 65.1-70.4 57.7-62.4 53.5-58.5 45.9-50.4 38.8-42.9
  67.9 (1.86) 59.9 (1.47) 55.6 (1.76) 47.8 (1.67) 41 (1.42)
Put 42.4-53.4 59.9-65.7 65.9-70.2 55.4-63.5 39.7-46.6
  47.8 (3.45) 63.6 (1.97) 68.1 (1.61) 59.9 (2.96) 42.9 (2.1)
Ser 91.3-97.7 76.6-80.8 62.6-68.6 45.8-50.1 34.3-41.4
  94.3 (2.03) 78.6 (1.38) 65.6 (1.86) 47.6 (1.63) 38.4 (2.3)
Pro 75.9-83 66.1-73.9 61.4-66.5 54.2-61.1 42.8-48.9
  78.2 (2.22) 70.1 (2.84) 63.4 (2.05) 58.4 (2.51) 46.5 (1.97)
Val 18.8-23.2 31.7-36.1 25.2-29.4 39.9-44.5 14.6-18.9
  21.3 (1.62) 33.9 (1.35) 27.2 (1.53) 41.9 (1.56) 16.7 (1.34)
Thr 31.9-37.3 49.7-55.2 73.9-79 61.3-65.9 41.1-45.5
  35 (2.14) 52 (1.79) 75.7 (1.78) 63.6 (1.65) 42.9 (1.58)
Leu 51.2-56.5 41.5-45.6 33.7-37.2 30.8-35.4 27.1-30.2
  53.6 (1.93) 43.2 (1.26) 35.7 (1.15) 32.6 (1.56) 28.5 (1.1)
Ile 50.5-56.9 45.2-49.1 39.5-42.1 30.7-34.7 25-28.8
  53.7 (1.98) 47 (1.34) 40.8 (1.0) 32.6 (1.66) 27 (1.34)
Cys 29.2-46.8 55.7-61.5 30.7-37.3 71.7-76.8 23.5-29.2
  42.8 (2.24) 57.8 (2) 33.3 (2.28) 73.7 (1.71) 25.7 (1.88)
Asn 28.1-35.3 64.5-71.1 50.1-57.5 43.7-49.7 23.9-29.1
  32.5 (2.74) 67.4 (2.15) 54.1 (2.4) 46.4 (2.29) 26.1 (1.83)
Asp 19-27 39.9-47.7 62-66.7 49.6-57.8 29.8-36.4
  23.1 (3.23) 43.7 (2.67) 64.2 (1.63) 53.4 (2.64) 33.6 (2.61)
Lys 37.4-46.8 59.7-65.4 33.6-39.6 50.6-55.9 23.7-28.7
  43.2 (2.78) 61.9 (1.91) 36.5 (1.88) 53.7 (1.78) 26.1 (1.91)
Gln 23.4-33.8 18.4-24.7 56.4-62 47.7-50 74-79.2
  28.9 (3.5) 21.2 (2.08) 59 (1.82) 46.1 (2.21) 77 (1.99)
Glu 22-29.9 45.1-51.7 66.7-74.1 53-60.3 33.4-40.5
  26.1 (2.87) 47.7 (2.15) 69.5 (2.82) 57.7 (2.7) 36.4 (2.29)
Met 35.2-41.7 51.2-56.4 28.9-34 60.6-65.5 17.9-22.9
  38.4 (2.4) 53.2 (1.74) 31.3 (1.69) 63.7 (1.68) 20 (1.8)
Spd 37.5-46.5 53.7-59 58.8-63.7 50.3-56.2 35.1-40.7
  42.4 (2.85) 56.6 (1.59) 60.6 (1.55) 53.3 (2.31) 38.1 (1.82)
His 52.9-61.2 65.9-69.9 42.6-47.4 73-77.5 33-38
  57.2 (2.49) 67.6 (1.45) 45.1 (1.55) 75.4 (1.42) 35.2 (1.71)
Phe 23-31.7 19.5-25.5 49.5-53.2 37.5-42.7 62.1-66.9
  28.4 (3.01) 22 (1.95) 51.4 (1.43) 39.9 (1.72) 63.9 (1.72)
Arg 43.3-53 58.8-62.9 40.2-44.2 75.9-81.4 31.5-36.3
  47.8 (2.81) 61 (1.51) 42.1 (1.47) 79.1 (1.84) 33.7 (1.53)
Tyr 35.1-44.6 46.8-52.6 29.5-33.5 75-80.6 21.5-26.3
  40.5 (3.18) 50.5 (1.89) 31.7 (1.72) 76.9 (2.01) 23.7 (1.76)
Trp 18.7-26.1 31.8-35.8 36-40 28.7-34.2 16.9-21
  22.2 (2.51) 34.3 (1.29) 37.7 (1.74) 31.4 (1.92) 18.5 (1.57)
Spm 33.4-41.5 47.2-51.8 52-55.4 43.5-49.6 31.5-36.6
  37.4 (2.48) 50.1 (1.58) 53.7 (1.29) 47.1 (2.03) 33.5 (1.74)
H Healthy volunteers, Pv Pemphigus vulgaris patients, P Psoriasis patients, L Leishmania patients, E Eczema patients, n Number of samples analysed
Table 4: Quantitative analysis of amino acids and polyamines in skin samples with range (μg/g), mean values (standard deviation).