Conditions: 100 mM phosphate buffer pH 9.3, capillary: 64.5 cm x 50 μm i.d., leff: 56.5 cm, 60 mbar s, +10 kV, λ= 200 nm.
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| Figure 1: CZE separations of rituximab. The 10 mg/ml pharmaceutical product MabThera was tenfold diluted with water and the samples were injected within
5 min (a,), in 3 days (b,) and 7 days (c,) after the dilution. Conditions: 100 mM phosphate buffer pH 9.3, capillary: 64.5 cm x 50 μm i.d., leff: 56.5 cm, 60 mbar s, +10 kV, λ= 200 nm. |
