Residual Solvents % Signal increased by trichlormethiazide amount
0 (mg/mL)* 500 (mg/mL) 1000 (mg/mL)
Ethanol 100% 124% 140%
Isopropanol 100% 129% 150%
1-Butanol 100% 117% 134%
tert-Butanol 100% 133% 157%
Methylene chloride 100% 124% 142%
Chloroform 100% 135% 166%
Table 5:Enhancement of HS-GC signal of residual solvents in tolnaftate sample solution by spiking of trichlormethiazide. *The concentration of residual solvents is 300 ppm each, and tolnaftate concentration is 500 mg/mL. The reported result is the average from three replicate measurements.