Type of study |
Study size |
Overall incidence of cancer or findings |
Cancer subtype |
Zhang et al. [79] cohort study |
7,950 T2DM subjects |
108.36/105 subjects in men; 870.2/105 subjects in women |
Pancreatic cancer liver cancer; kidney cancer breast cancer |
He et al. [80]
Meta-analysis |
2,596,856 T2DM Patients |
66.68-84.51 per 100,000 person-years |
Bladder cancer |
Yang et al. [81]
Meta-analysis |
643,683 DM patients; 4,819,656 non-DM patients |
Increased risk of cancer in DM patients compared to non-DM patients |
Bladder cancer |
Adami et al. [82]
Cohort study |
153, 852 T2DM patients |
819 incident cancers in 1-24 years |
Primary liver cancer, biliary tract cancer |
Chari et al. [83]
Cohort study |
2122 diabetic patients |
1% subjects diagnosed cancer in 3 years |
Pancreatic cancer |
Redaniel et al. [84]
Cohort study |
52,657 T2DM female patients |
A 29% overall cancer risk in DM patients; Positive association between diabetes and breast cancer |
Breast cancer |
Park et al. [85]
Retrospective study |
1213 men in which 408 subjects were obese |
Positive association between obesity and cancer |
Prostate cancer |
Larsson et al. [86]
Meta-analysis |
11,079 subjects |
Obese persons with increased risk of cancer |
Liver cancer |
Olsen et al. [87]
Meta-analysis |
28 studies |
Positive association between obesity and cancer |
Ovarian cancer |
Key et al. [88]
Prospective study |
624 obese subjects and 1669 controls |
Positive association between obesity and cancer |
Breast cancer |