Figure 1: The Figure contains comparison of pictures of colposcopy, cytology, and immunohistology staining of the cervical tissue (p16ink4a) of the patient No. 14 and 21 in Table 1. Patient No. 14: Cytology ASC-H: atypical squamous cells cannot HSIL exclude. Crowded sheet pattern, cells with degenerated enlarged slightly hyperchromatic nuclei, that show loss of polarity. The nuclei worrisome for a SIL with even contours. Many leucocytes, inflammation evidence. The chromatine irregularities are difficult to visualize. Histology result CIN1. Patient No 21: Smear cells with metaplastic cytoplasm showing variations in size, shape, and ratio of nucleolar to cytoplasmatic area. On the right in picture there are isolated small cells with variable N/C ratio. Some cells displayed prominent nuclear irregulations. Koilocytes on the right picture corner. Follow up histology was CIN2.