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Figure 3: A: Immunohistochemical detection of Aβ (1-40) in rat cerebral cortex in different experimental conditions. Scale bar size 100 μm. Control: untreated sample; Aβ: Aβ-injected cerebral cortex; Aβ+IBU-GSH: Aβ-injected cerebral cortex+IBU-GSH conjugate; C(-): negative control; arrows indicate Aβ(1-40) plaques, inserts show Aβ(1-40) plaques at higher magnification in Aβ and Aβ+IBU-GSH samples. B: Densitometric analysis of Aβ (1-40) positive area, expressed as % of positive area ± SD. Means are ± SD of three different consistent experiments. * Aβ+IBU-GSH conjugate vs Aβ: p < 0.05 |