Duodenal biopsy:
Histopathologicalfindings
Without Hp
n=211 (%)
Relation between chronic duodenitis and gastric Hp density
n=95 (%)
    64 +
(67.36)
20 ++
(21.05)
11 +++
(11.57)
p*
Chronic duodenitis 205 (97.2) 95 (31.0)       0.086
Mild
Moderate
Severe
101 (47.86)
93 (44.07)
11 (5.21)
41 (43.15)
46 (48.42)
8 (8.42)
               
Duodenal gastric metaplasia (DGM) 16 (7.5) 15 (15.78) 10 (10.52) 2 (2.1) 3 (3.15) 0.025
Incomplete
Intermediate
Complete
11 (5.21)
5 (2.36)
0
9 (9.47)
5 (5.26)
1 (1.05)
             
Active duodenitis 30 (14.2)   14 (14.7) 4 (4.21) 1 (1.05) 0.536
Duodenal HP 0 (0)   1 (1.05) 4 (4.21) 1 (1.05) 0.000
Alteration of villus height:crypt depth ratios 132 (62.6)   41 (43.15) 9 (9.47) 3 (3.15) 0.025
Crypt hyperplasia 81 (38.4)   23 (24.21) 3 (3.15) 0 (0) 0.003
Damage to the superficial enterocitos 38 (18)   28 (29.47) 7 (7.36) 4 (4.21) 0.001
Loss of the brush border 15 (7.1)     12 (12.63) 4 (4.21)   3 (3.15) 0.001
Abnormal count of intraepithelial lymphocytes 6 (2.8)   2 (2.1) 1 (1.05) 0 (0) 0.99
Duodenal ulcer 4 (1.9)   3 (3.15) 3 (3.15) 1 (1.05) 0.005
*p. χ2 of linear by linear trend. Intensity. Hp density: + mild, ++ moderate, +++ severe
Table 2: Bivariate analysis of the histopathological duodenal findings in cases with and without gastric Helicobacter pylori (Hp)