| |
Cases of significant IIBD score (>0.28) (n=33) |
Cases of non-significant IIBD score (0-0.28)(n=48) |
P-value |
| Age (y), range (mean) |
20-68 (44.0) |
19-63 (44.2) |
0.914* |
| Gender (male/female) |
28/5 |
42/6 |
0.990† |
| Serum total bilirubin, range (mean) |
0.35-2.19 (1.00) |
0.41-3.51 (0.92) |
0.499* |
| Serum AST, range (mean) |
15-363 (68.8) |
18-943 (95.9) |
0.344* |
| Serum ALT, range (mean) |
12-813 (92.6) |
13-2035 (166.8) |
0.214* |
| Serum ALP, range (mean) |
103-893 (311.8) |
144-1044 (274.9) |
0.319* |
| Serum LDH, range (mean) |
97-281 (189.3) |
123-552 (192.0) |
0.830* |
| Serum γ-GT, range (mean) |
12-1888 (188.8) |
16-419 (105.2) |
0.141* |
| Steatosis score |
0-3 (0.88) |
0-3 (0.88) |
0.988* |
| DR score (mean) |
0-3 (1.67) |
0-3 (1.48) |
0.416* |
| CK7+ hepatocyte score (mean) |
0-5 (2.03) |
0-4 (1.19) |
0.012* |
| Periportal CK7+ score (mean) |
0-1.0 (0.34) |
0-0.8 (0.15) |
0.007* |
| Peri-CV CK7+ score (mean) |
0-1.0 (0.29) |
0-1.0 (0.15) |
0.032* |
| Grading score in viral hepatitis cases (mean) [n=54] |
0-3 (1.75) [n=20] |
0-3 (1.50) [n=34] |
0.808* |
| Staging score in viral hepatitis cases (mean) [n=54] |
0-4 (1.75) [n=20] |
0-3 (1.79) [n=34] |
0.361* |
| Grading score in NASH cases (mean) [n=14] |
2-3 (2.50) [n=4] |
1-3 (1.60) [n=10] |
0.043* |
| Staging score in NASH cases (mean [n=14] |
2-3 (2.00) [n=4] |
1-3 (2.10) [n=10] |
0.827* |
IIBD: intraparenchymal isolated bile ductule; AST: aspartate aminotransferase;
ALT:alanine aminotransferase; ALP:alkaline phosphatase; CK7: cytokeratin 7;
CV: centrilobular vein; DR: ductular reaction; LDH:lactate dehydrogenase; γ-
GT: γ-glutamyltransferase; NASH, non-alcoholic steatohepatitis
*Unpaired t-test
†Chi-square test |
