Figure 7: A photomicrograph of a cross section in the jejunum of adult male albino rat of group IV (long term MTX treated group) showing:
a) shedding of most of cells covering the villi (arrows) with disappearance of the intervillous space. (H & E X 100)
b) shedding of most of cells covering the villi (black arrows), distortion of the crypts (Cr) and dilated blood vessel (blue arrow). (H & E X 100)
c) loss of the villi (black arrows), disappearance of the intervillous space and distortion of the crypts (Cr) with cellular infiltration (circle). (H & E X 200).
d) loss of villi (arrows) with distortion of some crypts (Cr). (H & E X 200).
e) loss of villi with cystic dilatation of the crypt (Cr) and multiple cellular shedding inside the crypts (blue arrows). (H & E X 200)
f) fusion of villi (circle) with flattening of surface epithelium (arrows) and distortion of the crypts (Cr). (H & E X 200).
g) ulceration (black arrows), dilated blood vessel (green arrow) and extensive cellular infiltration (CI). (H& E X 200).
h) showing loss of crypts architecture (Cr) and cellular vaculations (orange arrows). Few cells showed pyknosis (blue arrows) and karryorehxis (arrow heads) (H & E X400).