Figure 7: Electron micrograph of one year rats’ skin showing: (a) The stratum basale cells (B) with their nuclei and tonofilaments (t). The cells are attached to each other’s by desmosomes (*) and are attached via hemidesmosomes (H) to the well-developed basal lamina (arrowheads). Note collagen fibres (C) and vacuolations (V) of the cytoplasm of the basal cells (6000X). (b) Cells of stratum spinosum (S) with narrow intercellular spaces (*) in-between. A cell of stratum granulosum (G) contains keratohyalin granules (K). Note cells of stratum basale (B) (4000X). (c) A cell of stratum spinosum (S), Nucleus (N) of stratum granulosum cell and keratohyalin granules (K). Note the layers (C) of the stratum corneum cells (4000X). (d) Collagen fibres (C), fibroblast cell (F) and normal dermal mast cell (M) filled with granules (2500X).