Organ Histopathology scores of observation (mean) per each group Groups A B C D Kruskal-Wallis Test for global comparison of organ lesions among groups Asymptotic Significant (p<0.05) Liver Activated kupffer cells 0 0 0.50 ± 0.22 0.67 ± 0.21 0.39 Sinusodial widening 0 0 0.33 ± 0.21 0.67 ± 0.21 0.39 Cytoplasmic vacuolation 0 0 0.50 ± 0.22 0.67 ± 0.21 0.39 Karyorrlysis 0 0 0 0 1.00 Karyorrhexis 0 0 0 0 1.00 Mean score            0 0 0.27 ± 0.13 0.40 ± 0.13 0.39 Kidney Granular cast 0 0 0.33 ± 0.21 0.33 ± 0.21 0.39 Cellular cast 0 0 0.33 ± 0.21 0.33 ± 0.21 0.39 Protein cast 0 0 0 0 1.00 Pycnotic cell 0 0 0 0 1.00 Hydropic degeneration 0 0 0 0 1.00 Mean score 0 0 0.13 ± 0.08 0.13 ± 0.08 0.39 Group A: Normal diet (Control); Group B: Normal diet+700 mg/kg extract; Group C: Normal diet + 2100 mg/kg extract; Group D: Normal diet + 3500 mg/kg extract.

Table 1: Lesion scores of kidney and liver for all groups analyzed using Kruskal-Wallis test (Acute Toxicity).