Organ |
Histopathology scores of observation (mean) per each group |
Groups |
A |
B |
C |
D |
Kruskal-Wallis Test for global comparison of organ lesions among groups |
Asymptotic Significant (p<0.05) |
Liver |
Activated kupffer cells |
0 |
0 |
0 |
0 |
0.39 |
Sinusodial widening |
0 |
0 |
0 |
0 |
0.39 |
Cytoplasmic vacuolation |
0 |
0 |
0.33 ± 0.21 |
0.50 ± 0.22 |
0.39 |
Karyorrlysis |
0 |
0 |
0 |
0 |
1.00 |
Karyorrhexis |
0 |
0 |
0 |
0 |
1.00 |
Mean score |
0 |
0 |
0.17 ± 0.04 |
0.17 ± 0.04 |
0.39 |
Kidney |
Granular cast |
0 |
0 |
0 |
0.17± 0.06 |
0.39 |
Cellular cast |
0 |
0 |
0 |
0 |
1.00 |
Protein cast |
0 |
0 |
0 |
0 |
1.00 |
Pycnotic cell |
0 |
0 |
0.33 ± 0.21 |
0.50 ± 0.22 |
0.39 |
Hydropic degeneration |
0 |
0 |
0 |
0 |
1.00 |
Mean score |
0 |
0 |
0.07 ± 0.04 |
0.13 ± 0.06 |
0.39 |
Hydropic degeneration |
0 |
0 |
0 |
0 |
1.00 |
Mean score |
0 |
0 |
0.07 ± 0.04 |
0.13 ± 0.06 |
0.39 |
Group A: Normal diet (Control); Group B: Normal diet+70 mg/kg extract; Group C: Normal diet + 140 mg/kg extract; Group D: Normal diet + 210 mg/kg extract. |