| |
Patients reaching composite outcome (group A) |
Patients not reaching composite outcome (group B) |
P value |
| |
median |
25%-75% |
median |
25%-75% |
|
| Patient number (n) |
15 |
|
16 |
|
|
| Age (year) |
57.3 |
52.6 - 60 |
55.85 |
48.8 –62.23 |
0.861 |
| Gender F/M (n) |
5/10 |
|
5/11 |
|
1 |
| HTN (n, %) |
12 (80) |
|
11 (68.8) |
|
0.685 |
| DM (n, %) |
5 (33.3) |
|
7 (43.8) |
|
0.822 |
| HBV (n, %) |
1 (6.7) |
|
2 (12.5) |
|
1 |
| HCV (n, %) |
6 (40) |
|
2 (12.5) |
|
0.113 |
| Smoke (n, %) |
6 (40) |
|
7 (43.8) |
|
0.833 |
| BMI (kg/m2) |
27 |
20.8 - 30.6 |
24.9 |
22.75 - 26.78 |
0.338 |
| HD/PD (n) |
3-Dec |
|
13/3 |
|
1 |
| Dialysis duration (y) |
1 |
0.7 - 2.0 |
2 |
0.93 - 4.38 |
0.216 |
| Pathologic diagnosis |
|
|
|
|
0.302 |
| (1) Acute tubular injury (n, %) |
1 (6.7) |
|
4 (25) |
|
|
| (2) Mild cellular rejection (n, %) |
4 (26.7) |
|
4 (25) |
|
|
| (3) Severe cellular rejection (n, %) |
6 (40) |
|
7 (43.8) |
|
|
| (4) Antibody rejection (n, %) |
4 (26.7) |
|
1 (6.3) |
|
|
| Drug (Tacrolimus/Cyclosporin) |
14/1 |
|
13/3 |
|
0.6 |
| SBP (mmHg) |
129 |
120 - 144 |
132 |
120.5 - 150 |
0.379 |
| DBP (mmHg) |
74 |
60 - 82 |
81 |
70.75 - 93 |
0.11 |
| eGFR (biopsy) (ml/min) |
31 |
24 - 39 |
34.5 |
31.25 - 44.75 |
0.202 |
| eGFR (baseline) (ml/min) |
53 |
41 - 58 |
60 |
51 - 67.75 |
0.093 |
| eGFR (terminal) (ml/min) |
15.6 |
8.6 - 36.1 |
58.5 |
44.75 - 70.58 |
< 0.001* |
| SCr (biopsy) (mg/dl) |
2.2 |
1.8 - 2.8 |
1.8 |
1.7 - 2.28 |
0.216 |
| SCr (baseline) (mg/dl) |
1.4 |
1.3 - 1.8 |
1.2 |
1.1 - 1.4 |
0.066 |
| SCr (terminal) (mg/dl) |
3.3 |
2.0 - 6.8 |
1.2 |
1.03 - 1.6 |
< 0.001* |
| Hemoglobin (g/dl) |
10.8 |
9.6 - 13 |
11.65 |
8.88 - 13.43 |
0.892 |
| HbA1C (%) |
6.4 |
6.08 - 7.08 |
6.3 |
5.9 - 7.9 |
0.914 |
| Low-density lipoprotein (mg/dl) |
86.5 |
74.3 - 121.5 |
84 |
51 - 132 |
0.683 |
| Total cholesterol (mg/dl) |
161 |
132 - 187 |
179.5 |
112.5 - 243.25 |
0.682 |
| Triglyceride (mg/dl) |
112 |
93 - 181 |
138.5 |
113.5 - 269.25 |
0.318 |
| Albumin (mg/dl) |
3.5 |
3.15 - 3.75 |
3.8 |
3.6 - 4.1 |
0.025* |
| Uric acid (mg/dl) |
7.1 |
5.8 - 8.3 |
6.5 |
5.7 - 7.68 |
0.65 |
| Urine dipstick protein (mg/dL) |
|
|
|
|
0.296 |
| 0 mg/dL |
|
5 (33.3) |
10 (62.5) |
|
|
| 30-100 mg/dL |
|
7 (46.7) |
5 (31.25) |
|
|
| >100 mg/dL |
|
3 (20) |
1 (6.25) |
|
|
Composite outcome: first event with doubling of SCr or declining eGFR more than 30%
HTN, hypertension;DM, diabetes mellitus; HBV,hepatitis B; HCV, hepatitis C; BMI, body mass index; HD, hemodialysis; PD, peritoneal dialysis;SBP, systolic blood pressure; DBP, diastolic blood pressure; eGFR, estimated glomerular filtration; SCr: serum creatinine; HbA1C: hemoglobin A1c.
*: p<0.05 indicates significance |
|
