| |
Score |
Patients reaching composite outcome |
Patients not reaching composite outcome |
P value |
| (group A) |
(group B) |
| IFS |
Without |
5 (33.3) |
9 (60) |
0.143 |
| |
With |
10 (66.7) |
6 (40) |
|
| GFS |
Without |
12 (80) |
15 (100) |
0.224 |
| |
With |
3 (20) |
0 |
|
| IL23 (Gn)n |
Without |
6 (54.5) |
9 (81.8) |
0.361 |
| |
With |
5 (45.5) |
2 (18.2) |
|
| IL23 (Gn)c |
Without |
9 (81.8) |
5 (45.5) |
0.183 |
| |
With |
2 (18.2) |
6 (54.5) |
|
| IL23 (Ga)n |
Without |
12 (92.3) |
6 (100) |
1 |
| |
With |
1 (7.7) |
0 |
|
| IL23 (Ga)c |
Without |
10 (76.9) |
6 (100) |
0.517 |
| |
With |
3 (23.1) |
0 |
|
| IL23 (ATn)n |
Without |
15 (100) |
15 (93.8) |
1 |
| |
With |
0 |
1 (6.3) |
|
| IL23 (ATn)c |
Without |
0 |
1 (6.3) |
1 |
| |
With |
15 (100) |
15 (93.8) |
|
| IL23 (ATa)c |
Without |
0 |
1 (33.3) |
0.3 |
| |
With |
7 (100) |
2 (66.7) |
|
| IL23 (IT)c |
Without |
14 (93.3) |
11 (68.8) |
0.172 |
| |
With |
1 (6.7) |
5 (31.3) |
|
| IL23R (Gn)n |
Without |
4 (44.4) |
3 (30) |
0.65 |
| |
With |
5 (55.6) |
7 (70) |
|
| IL23R (Gn)c |
Without |
8 (88.9) |
8 (80) |
1 |
| |
With |
1 (11.1) |
2 (20) |
|
| IL23R (Ga)n |
Without |
9 (69.2) |
5 (71.4) |
1 |
| |
With |
4 (30.8) |
2 (28.6) |
|
| IL23R (Ga)c |
Without |
13 (100) |
5 (71.4) |
0.111 |
| |
With |
0 |
2 (28.6) |
|
| IL23R (ATn)n |
Without |
9 (60) |
8 (50) |
0.576 |
| |
With |
6 (40) |
8 (50) |
|
| IL23R (ATn)c |
Without |
2 (13.3) |
3 (18.8) |
1 |
| |
With |
13 (86.7) |
13 (81.3) |
|
| IL23R (ATa)n |
Without |
3 (50) |
3 (75) |
0.571 |
| |
With |
3 (50) |
1 (25) |
|
| IL23R (ATa)c |
Without |
1 (16.7) |
1 (25) |
1 |
| |
With |
5 (83.3) |
3 (75) |
|
| IL23R (IT)n |
Without |
10 (66.7) |
13 (81.3) |
0.433 |
| |
With |
5 (33.3) |
3 (18.8) |
|
| IL23R (IT)c |
Without |
10 (66.7) |
9 (56.3) |
0.552 |
| |
With |
5 (33.3) |
7 (43.8) |
|
Composite outcome: first event with doubling of SCr or declining eGFR more than 30%
IFS, interstitialfibrosis score; GFS, glomerular fibrosis score; (Gn)n, nuclear staining intensity of normal glomerulusmesangial cell; (Gn)c, cytoplasmic staining intensity of normal glomerulusmesangial cell; (Ga)n, nuclear staining intensity of atrophy glomerulusmesangial cell; (Ga)c, cytoplasmic staining intensity of atrophy glomerulusmesangial cell; (ATn)n, nuclear staining intensity of normal renal tubule; (ATn)c, cytoplasmic staining intensity of normal renal tubule; (ATa)n, nuclear staining intensity of atrophy renal tubule; (ATa)c, cytoplasmic staining intensity of atrophy renal tubule; (IT)n, nuclear staining intensity of interstitium; (IT)c, cytoplasmic staining intensity of interstitium.
p<0.05 indicates significance. |
|
