Figure 1: The findings of neck CT at surgery, or gross and microscopic examination of the resected high-grade chondrosarcoma specimen. (A) A full neck CT scan demonstrated a heterogeneously enhanced and poorly-demarcated mass (arrows) with focal calcification, measuring approximately 35 × 35 mm in diameter, arising possibly from the right cricoid cartilage or thyroid gland and projecting into the airway. Bar=1 cm. (B) The inadequate specimen from the percutaneous FNA cytology contained few individual cells or small clusters of tumor cells having pleomorphic and sometimes spindle- or multi-nuclei (inset), and abundant clear or vacuolated cytoplasm (lt., Papanicolaou stains), along with a substantial amount of metachromatic chondroid stroma (rt., Giemsa stain), without any evidence of necrotic or hemorrhagic backgrounds (lt.). Bars=100 μm (lt.) and 10 μm (rt.). (C)(D) Gross examination (C) of the resected laryngeal chondrosarcoma showed a multi-lobulated and firm mass with a grayish to whitish, fleshy and glistening appearance, involving the cricoid cartilage and cricothyroid muscle, and compressing the pre-existing right thyroid gland (rt. side). On its scanning magnification (H&E stains) (D), the tumor revealed a poorly-circumscribed, uncapsulated and basophilic cartilaginous mass lesion in a multi-lobulated fashion, aggressively invading the cricoid cartilage and cricothyroid muscle, but not the thyroid gland (rt. side) or covering tracheal epithelium (upper rt.). Bar=5 mm.