Inclusion criteria
1.Follicle stimulating hormone (FSH), luteinizing hormone (LH), oestradiol in the menopausal range (FSH>18 IU/L, LH>12.6 IU/L, and E2<361 pmol/l).
2. Patients with amenorrhoea for more than 12 months
3. Patient with at least 14 hot flushes or night sweats per week
4. Patient able to give written or witnessed oral informed consent prior to study star and able to comply with study requirements
Exclusion criteria
1. Patients with a history of using any form of hormonal replacement therapy within 8 weeks
2. Patients with a history of using Chinese medicine or other therapies which may affect the outcome within 8 weeks
3. Patients who in the judgment of the investigator will be unable to comply with protocol requirements
4. Patients with significant gastrointestinal, renal, hepatic, bronchopulmonary, neurological, cardiovascular, breast or endometrial carcinoma, or allergic diseases
5. Patients with uncontrolled hypertension
6. Patients with undiagnosed vaginal bleeding
7. Patients with a history of significant drug hypersensitivity
|
Inclusion criteria
1. Follicle stimulating hormone (FSH), luteinizing hormone (LH), oestradiol in the menopausal range (FSH>18 IU/L, LH>12.6 IU/L, and E2<361 pmol/l)
2. Patients with amenorrhoea for more than 12 months
3. Never received treatment for menopausal symptoms
4. Never received menopausal hormone therapy
5. Reporting a minimum of 14 hot flushes per week at the time of entry into the study
6. Patient able to give written or witnessed oral informed consent prior to study star and able to comply with study requirements
Exclusion criteria
1. Patients with a history of using Chinese medicine or other therapies which may affect the outcome within 8 weeks
2. Patients who in the judgment of the investigator will be unable to comply with protocol requirements.
3. Patients with significant gastrointestinal, renal, hepatic, bronchopulmonary, neurological, cardiovascular, breast or endometrial carcinoma, or allergic diseases
4. Patients with uncontrolled hypertension
5. Patients with undiagnosed vaginal bleeding
|
