CRC ADENOMAS Gender Male 12 5   Female 8 5 Age: mean (range)   67.9 (54-85) 62.6 (51-81) Site Proximal 7 2   Distal 12 5   Rectum 1 3 Stage I 2     II 9     III 5     IV 4   Differentiation Well 4     Moderate 14     Poor 2   Dysplasia Low Grade   5   High Grade   5

Table 1: Clinico - pathological features of patients affected by CRC or Adenoma and selected for immune-histochemical examination of μ-protocadherin expression and methylation analysis of its upstream control region