| |
CR (n= 77) n (%) |
PD (n= 33) n (%) |
ptotal# |
p |
OR |
95%CI |
| rs3136176 |
| Genotype |
| [AA]
[AT]
[TT] |
46 (59.7)
22 (28.6)
9 (11.7) |
13 (39.4)
16 (48.5)
4 (12.1) |
ns1 |
referent |
| 0.035
0.76 |
2.51
0.64 |
1.06 – 6.27
0.17 – 2.40 |
| Allele |
| [A]
[T] |
114 (74.0)
40 (26.0) |
42 (63.6)
24 (36.4) |
|
0.12 |
0.61
1.63 |
0.33 – 1.14
0.88 – 3.02 |
| Dominant model |
| [AA] + [AT]
vs.
[TT] |
68 (88.3)
9 (11.7) |
29 (87.9)
4 (12.1) |
|
0.80* |
0.96
1.00 |
0.27 – 3.33
0.30 – 3.66 |
| Recessive model |
| [TT] + [AT]
vs.
[AA] |
31 (40.3)
46 (59.7) |
20 (60.6)
13 (39.4) |
|
0.05 |
2.28
0.48 |
0.99 – 5.26
0.19 – 1.00 |
| rs1799798 |
| Genotype |
| [GG]
[GA]
[AA] |
56 (72.7)
17 (22.1)
4 (5.2) |
26 (78.8)
7 (21.2)
0 (0.0) |
ns2 |
referent |
| 0.81
0.43 |
0.89
– |
0.33 – 2.40
– |
| Allele |
| [G]
[A] |
129 (83.8)
25 (16.2) |
59 (89.4)
7 (10.6) |
|
0.28 |
1.63
0.61 |
0.67 – 3.99
0.25 – 1.50 |
| Dominant model |
| [GG] + [GA]
vs.
[AA] |
73 (94.8)
4 (5.2) |
33 (100.0)
0 (0.0) |
|
0.61* |
–
– |
–
– |
| Recessive model |
| [AA] + [GA]
vs.
[GG] |
21 (27.3)
56 (72.7) |
7 (21.2)
26 (78.8) |
|
0.50 |
0.72
1.39 |
0.27 – 1.90
0.53 – 3.69 |
| ^– p-value afterBonferroni correction
* – p-value after Yate’s correction
# – global p-value for genotype
1 - χ2= 4.438183, df= 2, p= 0.108815
2 - χ2= 1.836043, df= 2, p= 0.399375 |
|
