| Variables |
Cases (N=172) |
Controls (N=154) |
Pa |
| Age, mean(SD) |
62.2 (10.0) |
61.7 (11.0) |
0.660 |
| Sex, N (%) |
| Male |
163 (94.8) |
137 (89.0) |
|
| Female |
9(5.2) |
17(11.0) |
0.053 |
| Smoking status, N (%) |
| Never |
41 (23.8) |
74 (48.0) |
|
| Former |
92 (53.5) |
60 (39.0) |
|
| Current |
39 (22.7) |
20 (13.0) |
<0.001 |
| Never |
41 (23.8) |
74 (48.0) |
|
| Ever |
131 (76.2) |
80 (52.0) |
<0.001 |
| Pack-years, mean(SD) |
70.2 (68.1) |
49.4 (63.2) |
0.030 |
| Range of pack-years, N (%) |
| None |
41 (23.8) |
74 (49.0) |
|
| <45 |
57 (33.1) |
48 (31.8) |
|
| ≥45 |
74(43.1) |
29 (19.2) |
<0.001 |
| BMIb, N(%) |
| <25 |
62 (39.7) |
46 (30.3) |
|
| 25-30 |
60 (38.5) |
62 (40.8) |
|
| ≥30 |
34 (21.8) |
44 (28.9) |
0.163 |
| Family history of all cancers, N (%) |
| No |
23 (13.4) |
29 (18.8) |
|
| Yes |
149 (86.6) |
125 (81.2) |
0.179 |
| Family history of esophageal cancer, N (%) |
| No |
164 (95.3) |
145 (94.2) |
|
| Yes |
8(4.7) |
9 (5.8) |
0.629 |
| GERD, N (%) |
| No |
61 (35.5) |
128 (83.1) |
|
| Yes |
111 (64.5) |
26 (16.9) |
<0.001 |
| BE, N (%) |
| No |
103 (60.2) |
151 (98.1) |
|
| Yes |
68 (39.8) |
3(1.9) |
<0.001 |
|
| Table 1: Distribution of host characteristics by case-control status .
Abbreviations: SD- Standard Deviation; BMI-Body Mass Index;
GERD- Gastroesophageal Reflux Disease; BE-Barrett’s Esophagus;
TM- Tail Moment; BPDE, benzo[a]pyrene diol epoxide. aP values were
derived from χ2 test for categorical data (i.e. sex, ethnicity, smoking
status, family history of cancer, family history of esophagus cancer,
GERD status, BE status), from the Student t-test for continuous
variables (i.e. age ) and from the Wilcoxon rank-sum test for packyears.
bBMI of three years prior to cancer diagnosis for EAC patients
and interview for control participants. |
