Characteristics of each study

First Author	Year	Country	Cancer	Genotyping Methods	Source of controls	Groups	R462Q Genotypes			Total	HWEa	Ref.
First Author	Year	Country	Cancer	Genotyping Methods	Source of controls	Groups	RR	RQ	QQ	Total	HWEa	Ref.
Barbison	2011	Argentina	Cervical	Pyrosequencing	HB	Controls	44	57	22	123	0.64	[22]
						Cases	44	48	6	98
Beuten	2010	USA	Prostate	Taqman Assay	HB	Controls	126	91	7	224	0.05	[24]
						Cases	75	64	17	156
San Francisco	2014	Chile	Prostate	Taqman Assay	PB	Controls	11	6	4	21	0.11	[12]
						Cases	43	31	9	83
Zabala	2009	Venezuela	Prostate	PCR-ASA	HB	Controls	34	16	2	52	0.95	[23]
						Cases	37	10	4	51

Abbreviation: HB: Hospital Base; PB: Population Based; PCR-ASA: Polymerase-Chain Reaction Allelic Specific Amplification; HWE: Hardy-Weinberg Equilibrium. aThe Hardy-Weinberg Equilibrium was calculated by the 2-test, values greater than 0.05 are consider to agree

Table 1: Characteristics of each study included in the meta-analysis.