Pre-treatment ROS challenge aExperiment series 1 bExperiment series 2 Control 0 13.0 ± 1.5 7.0 ± 1.2 300 μM 24.7 ± 0.9 20.3 ± 1.2 Quercetin 0 6.0 ± 0.6 4.3 ± 0.3 300 μM 8.7 ± 1.2 9.3 ± 0.9 aExperiment series 1 was conducted to investigate Calendula extracts A and B. bExperimentseries 2 was conducted for extracts C and D.

Table 2: Effect of Quercetin pre-treatment and the media control on MN/1000 binucelated cells. It is shown the number of micronuclei/1000 bionucleated of control and quercetin after treat cells with or without H2O2.