Variables No. of patients MGMT TP53 CDKN2A     M U M U M U Age               ≤40 years 25 17 8 8 17 9 16 >40 years 23 19 4 6 17 8 15 Position               Frontal 31 24 7 10 21 13 18 Others 17 12 5 4 13 4 13 Grade & type             III AOD 15 10 5 7 8 8 7 AOA 11 9 2 3 7 3 8 AE 3 1 2 0 3 0 3 AA 2 2 0 0 3 0 2 Total 31 22 9 10 21 11 20 IV- GB 17 14 3 4 13 6 11 Post-surgery treatment           CT+RT 21 17 4 6 15 9 12 RT 9 7 2 3 6 1 8 No 18 12 6 5 11 7 11

Table 1: Patient characteristics (Age, Position, Grade, Histology type, and Treatment information) wise Individual Methylation status of MGMT, TP53 and CDKN2A.