Table 1

Drugs or Inhibitors	Targets	Pathways	Cancer Models	Ref.
Debromohymenialdisine	Chk1/2	Cell cycle and DNA repair	Glioblastoma	[37]
AZD7762 (AstraZeneca)	Chk1/2	Cell cycle and DNA repair	Colon cancer	[40]
CP4666722 (Pfizer)	ATM	Cell cycle and DNA repair	Breast cancer	[46]
Cyclopamine	SMO	Hh signaling pathway	Esophageal cancer, Glioblastoma	[60] [65]
Forskolin	GLI1	Hh signaling pathway	Esophageal cancer	[60]
GSIs, DAPT	g-secretase	Notch signaling pathway	Glioblastoma	[90] [123]
YM155	survivin	Wnt signaling pathway	Non-small cell lung cancer	[107]
Perifosine	AKT	PI3K/AKT signaling pathway	Medulloblastoma	[126]

Table 1: Drugs or inhibitors already available which can sensitize CSCs to radiotherapy.