| Interacting protein |
Mechanism |
Function |
Reference |
| N-myc |
Binds to intron 2 |
Regulates transcription of nestin |
[40] |
| SOX1/2/3 |
Binds to intron 2 |
Regulates transcription of nestin |
[46] |
| SOX11 |
Binds to intron 2 |
Regulates transcription of nestin |
[46] |
| Class III POU |
Binds to intron 2 |
Regulates transcription of nestin |
[46] |
| Oct4 (Class V POU) |
Binds to intron 2 |
Regulates transcription of nestin |
[47] |
| Vimentin |
Binds nestin |
Copolymerization |
[48] |
| α-internexin |
Binds nestin |
Copolymerization |
[36] |
| Cdk5 |
Binds and phosphorylates Thr316 and Thr1495 of rat nestin |
Regulates the interaction of nestin and p35 |
[55] |
| Cdk5 |
Not determined |
Regulates the expression of the nestin protein |
[56] |
| cdc2 kinase |
Phosphorylates Thr316 of rat nestin |
Reorganization during mitosis |
[57] |
