| Assumed properties of transport kinetics |
|
Predicted effect on transport |
|
First in, last out
|
Rate-limiting step
|
Inhibition by H+
|
Inhibition by Lac-
|
| Proton (H+) |
binding/release of H+ |
Yes |
Yes |
| |
binding/release of Lac- |
Yes |
No |
| |
translocation of empty carrier |
Yes |
No |
| |
translocation of loaded carrier |
Yes |
No |
| Lactate (Lac-) |
binding/release of H+ |
No |
Yes |
| |
binding/release of Lac- |
Yes |
Yes |
| |
translocation of empty carrier |
No |
Yes |
| |
translocation of loaded carrier |
No |
Yes |
