Dopamine receptor

β2-Adrenergic receptor Histamine H1 Receptor M3 Muscarinic Acetylcholine Receptor Mu-Opioid Receptor a Lipid GPCR M2 Muscarinic Acetylcholine receptor Kappa-Opioid receptor ¬†Delta-Opioid receptor Neurotensin 1 receptor¬† Chemokine receptor 1 Protease activated receptor 1 5-hydroxy tryptamine¬† receptor 1B 5-hydroxy tryptamine receptor 2B
  Seq TM Seq TM Seq TM Seq TM Seq TM Seq TM Seq TM Seq TM Seq TM Seq TM Seq TM Seq TM Seq TM Seq TM
α2a_HUMAN 34% 49% 31% 42% 27% 32% 28% 31% 27% 34% 24% 26% 25% 29% 24% 33% 27% 32% 22% 26% 17% 25% 20% 25% 31% 39% 28% 37%
α2b_HUMAN 32% 49% 28% 41% 26% 33% 26% 29% 26% 34% 24% 28% 24% 27% 24% 35% 27% 32% 19% 26% 16% 30% 18% 28% 28% 37% 29% 41%
α2c_HUMAN 34% 49% 29% 42% 28% 37% 26% 30% 27% 37% 24% 30% 24% 30% 24% 33% 25% 32% 19% 27% 20% 29% 18% 26% 31% 38% 26% 39%
Table 1: Comparison of sequences identities of α-2 ARs with crystal structures of Dopamine Receptor, β2- adrenergic receptor, Histamine H1 receptor, M3 Muscarinic Acetylcholine receptor, Mu-Opioid Receptor, a Lipid GPCR ( Results are based on BLAST and BLAST- 2 Analysis).