RK4

 

RKF

 

TR-

BDF2

Rosen-

brock

IMEX

 

JVODE

ADAMS

JVODE

BDF

JLSODE

 

Protocol 1 (single pulse)

Tol1

1.0

1.19e-3

5.66e-3

5.32e-4

5.27e-4

5.74e-4

8.62e-4

4.88e-4

Tol2

1.0

1.98e-3

2.11e-2

6.49e-4

6.06e-4

1.05e-3

1.47e-2

8.88e-4

ΔP1 Tol1/Tol2

-

7.9e-4

1.54e-2

1.17e-4

7.9e-5

4.76e-4

1.38e-2

4e-4

Protocol 2 (repeated pulses)

Tol1

1.0

1.95e-3

6.12e-3

6.07e-4

5.87e-4

7.48e-4

1.95e-3

7.53e-4

Tol2

1.0

2.09e-3

1.86e-2

1.03e-3

8.8e-4

2.46e-3

3.07e-2

1.7e-3

ΔP2 Tol1/Tol2

-

1.4e-4

1.25e-2

4.23e-4

2.93e-4

1.71e-3

1.12e-2

9.47e-3

ΔTol1 P1/P2

-

7.6e-4

4.6e-4

7.5e-5

6e-5

1.74e-4

1.08e-3

2.65e-4

ΔTol2 P1/P2

-

11e-4

2.5e-3

3.81e-4

2.74e-4

6.6e-4

1.6e-2

8.12e-4

Tol1 and Tol2 represent the ||p|| norm value for each algorithm with P1 and P2 protocols. ΔP1 Tol1/Tol2 represents the absolute difference between Tol1 and Tol2 for P1, whereas ΔP2 Tol1 / Tol2 represents the same absolute difference for P2. ΔTol1 P1/P2 represents the absolute difference between P1 and P2 for Tol1 parameters, whereas ΔTol2 P1/P2 represents the same absolute difference for Tol2.
Table 6: Quantiļ¬cation and comparison of normalized solver performances for the GABAA model.