Topological parameter 
Human 
Sea urchin 
C. elegans 
Connected components 
1 
1 
1 
Number of nodes 
151 
130 
102 
Number of edges 
205 
184 
139 
Clustering coefficient 
0.028 
0.037 
0.031 
Network diameter 
20 
23 
23 
Shortest paths 
8086 (35%) 
7176 (42%) 
3524 (34%) 
Characteristic path length 
6.546 
7.967 
7.812 
Averaged number of neighbours 
2.662 
2.738 
2.569 
Indegree distribution 



γ 
1.499 
1.531 
1.826 
r 
0.988 
0.989 
0.996 
R^{2} 
0.884 
0.700 
0.914 
Outdegree distribution 



γ 
1.934 
2.228 
2.345 
r 
0.996 
0.967 
0.931 
R^{2} 
0.818 
0.919 
0.843 
Avg. Clustering Coefficient Distribution 



γ 
0.454 
0.690 
0.416 
r 
0.183 
0.347 
0.305 
R^{2} 
0.217 
0.420 
0.135 
The value of connected components measures the number of networks obtained; the number of nodes represent the total number of molecules involved; the number of edges represents the total number of interaction found; the clustering coefficient is calculated as CI = 2nI / k(k −1), where nI is the number of links connecting the kI neighbors of node I to each other; the network diameter is the largest distance between two nodes; shortest paths is the measure of the number (and percentage) of shortest path within the network; the Averaged n° neighbours represent the mean number of connection of each node; the Char. path length gives the expected distance between two connected nodes; γ represent the exponent of power law y = ax^{γ}, r is the correlation coefficient, R^{2} the coefficient of determination of power law. 