Figure 8: Effect of co-administration of mitomycin C and cisplatin with or without the administration of B.aristata on phospholipid composition of liver mitochondria. The animals were divided into four groups of six animals each. Group-1, received saline, group-2, received a single dose of mitomycin C (2 mg/kg body weight, i.p.) and cisplatin (12 mg/kg body weight, i.p). Rats were sacrificed 48 h after the administration of drugs. Group-3, received alcoholic extract of B.aristata (10 mg/100 g body weight, oral) for three days. Group-4 received alcoholic extract of B.aristata (10 mg/100 g body weight, oral) for three days, followed by single dose of mitomycin C (2 mg/kg body weight, i.p) and cisplatin (12 mg/kg body weight, i.p). Rats were sacrificed 48 h after the administration of drugs. All the values are expressed relative to the control, which is taken as 100. The control values of are 24 1.8, 32 2.0, 26 1.2 and 36 1.0 for total phospholipids, phosphatidylcholine, phosphatidylethanolamine and cardiolipin respectively. Values are Mean SD for at least 13 animals. *p<0.05, **p<0.01 and ***p<0.001.