| |
Control (n=6) |
Vehicle (n=6) |
Boldine (n=8) |
| Coagulative necrosis |
5/6 (83,3%) |
6/6 (100%) |
5/8 (62,5%) |
| Intratumoral hemorrhage |
6/6 (100%) |
6/6 (100%) |
6/8 (75%) |
| Vascular proliferation |
6/6 (100%) |
6/6 (100%) |
7/8 (87,5%) |
| Microabscess |
3/6 (50%) |
4/6 (66,6%) |
2/8 (25%) |
| Lymphocytic infiltration |
6/6 (100%) |
6/6 (100%) |
6/6 (100%) |
| Peripheral pseudopalisading |
3/6 (50%) |
3/6 (50%) |
5/8 (62,5%) |
The histological variables were regarded as present or absent. (n = number of
animals per group) |