| Adverse Effect |
Symptoms |
Frequency (n=71) |
Relative frequency (%) |
| Gastrointestinal |
Diarrhea, nausea, vomiting, loss of appetite |
56 |
79 |
| Dermatologic |
Rash, redness, itching, peeling skin, hand-foot skin reaction (redness, pain, swelling or blisters on the palms of the hands or soles of the feet), wound healing problems |
54 |
76 |
| Metabolic |
Weight gain or weight loss, edema |
43 |
61 |
| Pain |
Skin pain, Pain in the stomach |
32 |
45 |
| Cardiovascular |
High blood pressure, failure of cardiac output, QT prolongation |
24 |
34 |
| Anemia |
|
22 |
31 |
| Neuropathy |
Pathologic skin sensations (tingling, burning, numbness) |
18 |
25 |
| Thrombocytopenia |
|
15 |
21 |
| Leukopenia |
|
13 |
18 |
| Neutropenia |
|
10 |
14 |
|
