Combined genotype (MTHFR gene) Controls, n=79 CCR, n=73 Gastric cancer, n=33 P value OR 95%CI
CA/CA 19 17 13 0.10**  
CA/CC 18 10 4 0.08*  
CA/TA 17 27 10 0.035*** 0.47 (0.21-10.1)
CA/TC or CC/TA 15 10 4    
CC/CC 4 2 1    
CC/TC 1 2 0    
TA/TA 3 3 1    
TA/TC 1 2 0    
TC/TC 1 0 0    
P* value was calculated with CA/CC versus other genotypes, between CCR+GC compared with controls P** value was calculated with CA/CA versus other genotypes, between GC compared with controls P*** value was calculated with CA/TA versus other genotypes, between CCR compared with controls
Table 3: MTHFR C677T and A1289C combined genotype in gastrointestinal cancer.