![]() |
Figure 7: The effect of 5-dAza and rotenone on mitochondria membrane polarization and their network in the hNSCLC. Panel A shows polarization of mitochondrial network of control cells cultured in standard conditions. 24-hours treatment of the cells with 5 μM 5-dAza (B) and 1 μM rotenone (C) reduced mitochondrial membrane polarization and disrupted mitochondrial network. A simultaneous application of both the agents (D) reversed the toxic effect. |