Figure 2: Infection of AdhVASH1 in HM-1 augmented tumor angiogenesis in the peritoneum. A: HM-1/LacZ or HM-1/hVASH1 cells were inoculated into the peritoneal cavity of mice (N=4). Eleven days after the inoculation, the peritoneum was inspected. The sagittal section of peritoneum was stained with hematoxylin and eosin. Scale bar=200 μm. B: The thickness of peritoneal tumor was measured and compared between HM-1/LacZ (N=5) and HM-1/hVASH1 (N=5) groups. Means and SDs are shown. C: Microvessels of the peritoneum were immunostained with anti-CD31 Ab. Scale bar=200 μm. D: CD31-positive vascular area was quantified and compared between HM-1/LacZ (N=6) and HM-1/hVASH1 (N=4) animals. Means and SDs are shown.