Figure 1: Relative fold induction of (A) MDR1 gene post treatment with vinblastine alone and in the presence of different concentrations of ritonavir, (B) MRP2, (C) CYP3A4 and (D) PXR genes post treatment with vinblastine alone and in the presence of optimized concentration of ritonavir on LS180 cells. Values represent mean ± SD (n=4). A P-value of less than 0.05 was considered to be statistically significant and represented by *.