Figure 2: Inhibition of cell survival of Jurkat cells by simvastatin, manumycin A, and YM-53601. Jurkat cells were cultured in RPMI-1640 media at pH 7.5 or 6.7 for 5 days with simvastatin, manumycin A, or YM-53601 at the concentrations indicated, and cell survival was measured as described in the legend of Figure 1B. The mean values and S.D. obtained from three experiments using different cultures are represented. S.D. less than 10% is not represented. The p values at pH 6.7 compared with data at pH 7.5 were calculated. *p< 0.01; no mark, p>0.01.