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Figure 6: Comparative expression analysis of miR-138 in 18 paired samples and miR-98 in 22 paired samples of FFPE cell blocks of tumor and normal tissue from PTC patients’ individually using qRT-PCR. Combined data for both races (A and C) and race-specific data (B and D) is presented. No clear trend was present for miR-98 expression in CA. However, in AA, 80% of tumors had down-regulated miR-138 (Figure 6B). The miRNAs expression was normalized using RNU48 miRNA. P values represent comparison between normal and tumor (6A, 6C), and CA tumor vs AA tumor (6B, 6D) using F test. |