Figure 2: Relationship between toxicities and dose of LEC/chTNT-3. A) Incidences of new or worsening cases of gastrointestinal toxicities during the initial 28 days of the study are not dependent on LEC/chTNT-3 dose. B) Incidences of new or worsening cases of neutropenia (all grade ≤ 2) showed a trend of dose dependency (p=0.08). Trends for dose dependency were analyzed using the chi-square test for trend.