| Study |
Year |
Factors significantly associated wtih increased survival time in multivariate analysis (p value) |
| Kilburn |
2014 |
none found |
| Peterson |
2014 |
KPS>80, absence of prior WBRT |
| Jung |
2013 |
favorable RTOG RPA class, single metastasis |
| Sengoz |
2013 |
none found |
| Kawabe |
2012 |
favorable KPS (0.001), single metastasis (0.012), well controlled primary (0.021) |
| Leeman |
2012 |
none found |
| LI |
2012 |
NR |
| Lin |
2012 |
none found |
| Yoo |
2011 |
KPS > 70 (0.0001), RPA 1 or 2 (0.0014) |
| Valery |
2011 |
none found |
| Hatiboglu |
2011 |
smaller pre-SRS tumor volume (0.008), non-melanoma primary (0.002), no necrosis in pre-SRS MRI (0.04), female sex (0.03), BSBM 2-3 (0.007), SIR > 5 (0.003) |
| Kelly |
2011 |
none found |
| Koyfman |
2010 |
greater performance status (0.0009), smaller tumor volume (0.0128) |
| Samblas |
2009 |
NR |
| Lorenzoni |
2009 |
no WBRT (0.005), KPS > 80 (0.0025), primary tumor controlled (0.007), favorable BSBM (0.00015) |
| Kased |
2008 |
single metastasis (0.003), non-melanoma primary (0.003), extracranial disease controlled (0.058) |
| Hussain |
2007 |
NR |
| Fuentes |
2006 |
NR |
| Yen |
2006 |
limited systemic disease (0.0293) |
| Shuto |
2003 |
NR |
| Huang |
1999 |
no active extracranial systemic disease (0.0008) |