| Groups |
Age range |
%AF+ig/
%AF+ tc |
Sex
fem/masc |
Types and concentration (ng/mL) of aflatoxins excreted in urine, (number of cases) |
HPLC
ngAF/mg cr (N° + cases) |
ELISA
ngAF/mg cr (N°+ cases) |
| AFB1 |
AFM1 |
AFP1 |
AFB-Gua |
| Risk groups |
| HBV |
26-68 |
50/7 |
11/19 |
170 - 324
(3) |
2 - 90
(4) |
20 - 36
(3) |
1 - 43
(5) |
1 - 590
(6) |
0.1 - 1543
(15) |
| HCV |
34-64 |
17/2 |
19/11 |
0 |
1 - 44
(4) |
0 |
1 - 4
(4) |
2 - 63
(7) |
3 - 60 (8) |
| VC |
30-72 |
27/4 |
18/12 |
423 - 502
(2) |
14 - 101
(5) |
48 - 127
(2) |
0.4 - 323
(6) |
0.3 - 1693
(11) |
0 – 4106
(15) |
| Range |
26-72 |
10-50% |
48/42 |
170 - 502 |
1 - 101 |
20 - 127 |
0.4 – 323 |
0.3 -1693 |
0.1 - 4562 |
| N° positive cases |
5/210
(2.4%) |
13/210
(6.2%) |
5/210
(2.4%) |
15/210 (7.2%) |
24/210
(11.4%) |
38/210
(18.1%) |
| Control groups |
| AC |
41-74 |
10/1 |
10/20 |
0 |
0 |
0 |
1 - 2
(3) |
0.3 - 3
(2) |
1 - 10
(3) |
| KF |
35-71 |
3/1 |
17/13 |
0 |
0 |
0 |
0 |
0 |
2 |
| CNHD |
34-69 |
0/0 |
19/11 |
0 |
0 |
0 |
0 |
0 |
0 |
| H |
26-72 |
10/1 |
15/15 |
0 |
1 - 4
(3) |
2 - 3
(2) |
1
(1) |
1 - 10
(4) |
9 - 42
(6) |
| Total |
26-74 |
|
109/101 |
|
|
|
|
|
|
| N° positive cases |
0 |
3/210 (1.4%) |
2/210 (1.0%) |
4/210 (1.9%) |
6/210 (2.9%) |
9/210 (4.3%) |
| Statistical analyses |
| P value in F test* |
0.036 |
0.0532 |
0.0013 |
0.277 |
|
|
| Total number of 47 positive cases in 210 total number of samples |
5/210
(2.4%) |
16/210
(76.2%) |
7/210
(3.3%) |
19/210
(9.1%) |
|
|
| P values in contrastsa |
VC vs HBV : 0.036 |
VC vs H: 0.019
VC+HBV+
HCV vs H : 0.029 |
VC vs H : 0.002
HBV vs H :0.023
VC+HBV vs H: 0.0005 |
Non-significant at 0.05% |
|
|
|
| HBV : Viral B Hepatitis; HCV: Viral C Hepatitis; VC:Viral cirrhosis; AC:Alcoholic cirrhosis; KF:Kidney failure. CNHD: Chronic non hepatic diseases; % AF + ig/ % AF +
tc total cases: Percentage of aflatoxin positive cases inside the group of 30, between aflatoxin positive cases inside total 210 cases. *With data previously transformed
using Box & Cox method. a: Always lower averages in Healthy (H). (N° + cases): Number of positive cases |
| Table 1: Excretion of AF types in hepatic diseases, by HPLC and ELISA methods, and statistical analysis. |
