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Figure 4: Comparative expression analysis of miR-129-2-3p in 37 pancreatic cancer patient’s tumor specimens compared to 24 pooled normal samples of FFPE tissue blocks (4A), comparative expression analysis in 24 paired samples of FFPE tissue blocks of tumor and normal tissue samples from the same patient (4B) quantitated individually using qRT-PCR. The Kaplan-Meier curve and Log-ranks tests for miR-129-2-3p expression and survival of patients are also presented in 4C. There was a significant down-regulation of miRNA-129-2-3p in most of the tumor samples when compared to normal (4A). The miRNAs expression was normalized using RNU48 miRNA. P values represent comparison between normal and tumor paired samples (4B) using Wilcoxon matched pairs t test. |