Predictive Factor Clinical Benefit % P value Age > 65 versus < 65 89 versus 46 < 0.007 Prior metastatic treatment ; < 4 versus > 4 87 versus 25 < 0.0007 Hormone receptor status ER+/PR+ versus ER+/PR- 84 versus 42 < 0.05

Table 2: Predictive Factors of Clinical Benefit.