Biochemical markers Mean concentrations pre-vitamin D3 administration Mean concentrations 6 months post-vitamin D3 administration
Serum calcium (mg/dl) 9.4 ± 3.2 9.2 ± 4.2
Serum phosphate (mg/dl) 3.4 ± 0.4 3.7 ± 0.6
Serum alkaline phosphatase (IU/L) 74 ± 12.5 53 ± 7.5
Serum creatinine (mg/dl) 0.7 ± 0.3 0.7 ± 0.5
Intact parathyroid hormone (pmol/L) 62 ± 20* 32.6 ± 11.6*
Serum 25(OH)D3  (nmol/L) 17.52 ± 15** 109.44 ± 34.9**
24 hours urinary calcium (mg/24 hrs) 97.4 ± 73 119 ± 64
Table 2: The effects of vitamin D3 administration at 50,000 IU on the biochemical measures in 40 RR MS patients (31 females and 9 males), pre- and post-six months vitamin D3 administration. Data presented as mean ±SD; * P<0.05, **P<0.01.