Trace metal (μg/g tissue) Control group (Group I) (n=20) Group II (50 benign breast tumor patients) Group III (77 malignant breast tumor patients)
Non-metastatic (Group III a) Metastatic (Group III b)
Copper 0.65 ± 0.2 0.84 ± 0.28 2.35 ± 0.62 (a) 3.79 ± 0.69 (a, c)
3.07 ± 0.99 (a, b)
Zinc 13.85 ± 4.54 14.86 ± 2.36 18 ± 0.67 (a) 23.22 ± 3.6 (a, c)
20.71 ± 3.71 (a, b)
Manganese 0.25 ± 0.09 0.25 ± 0.1 0.26 ± 0.096 0.31 ± 0.122
0.3 ± 0.11
Iron 3.67 ± 0.95 6.56 ± 1.16 8.89 ± 1.03 (a) 11.65 ± 1.83 (a, c)
10.32 ± 2.04 (a, b)
(a) Significant against control group; (b) Significant against benign group; (c) Significant against non-metastatic cancer group; Significant at P<0.05
Table 1: Levels of different trace metals in breast tissue of the study groups (μg/g tissue).