No. (%) of Patients
Subtherapeutic Digoxin Level  (< 0.9 ng/mL) (n= 103) Therapeutic Digoxin Level (0.9-2.2 ng/mL) (n=88) Toxic Digoxin Level (>2.2 ng/mL) (n=26)
Any Symptoms & or ECG changes 95 (92.2%) 44(61.3%) 25 (96.2%)
Symptoms
  Anorexia 2 (1.9%) 1(1.3%) 2 (7.6%)
  Nausea 1 (1.9%) 0(0%) 6 (23.1%)
  Vomiting 5(4.9%) 2(2.2%) 5 (19.2%)
  Abdominal Pain 17 (16.4%) 1(1.3%) 5(19.2%)
  Diarrhea 1 (0.97%) 0(0%) 4 (15.3%)
  Dizziness 7(6.7%) 2(2.2%) 2 (7.6%)
  Headache 4 (3.8%) 2(2.2%) 1 (3.8%)
  Confusion 16 (15.5%) 0(0%) 0 (0%)
  Visual Changes 1(0.97%) 0(0%) 1 (3.8%)
  Palpitation 6(5.8%) 3(3.4%) 7 (26.9%)
  Cough 1(0.97%) 0(0%) 1(3.8%)
  Dyspnoea 10 (9.7%) 4(4.5%) 4(15.3%)
Electrocardiographic Changes
  Atrial Fibrillation 13 (12.6%) 8(9%) 7 (26.9%)
  Bradycardia (ᐸ50 beats/min) 5 (4.9%) 3(3.4) 2(7.6%)
  Junctional Tachycardia 0(0.0%) 1(1.3%) 0(0%)
  Sustained ventricular tachycardia 1(0.97%) 0(0%) 0(0%)
  Sinus arrest 4(3.8%) 0(0%) 1(3.8%)
  Heart block 0(0%) 1(1.3%) 4(15.3%)
Table 2: Frequency of Symptoms and or Electrocardiographic Changes in Patients with Abnormal Digoxin Concentration (n= 129)