| |
Therapeutic
SDC Group (n =88) |
Subtherapeutic
SDC Group (n=103) |
Toxic
SDC Group (n=26) |
| Total Group |
Total Group |
Total Group |
| Inpatient
(n= 77) |
Outpatient
(n=11) |
Inpatient
(n=84) |
Outpatient
(n=19) |
Inpatient
(n=23) |
Outpatient
(n=3) |
| SDL (ng/mL)
Mean ± SD |
1.19 ± 0.26 |
0.67 ± 0.17 |
2.75 ± 1.2* |
| 1.18 ± 0.59 |
126.6 ± 0.56 |
0.66 ± 0.4 |
0.52 ± 0.34 |
0.06 ± 0.8 |
1.06 ± 0.8 |
| All Groups (1.02 ± 0.8) |
| Blood urea nitrogen (mg/dl)
Mean ± SD |
62.6 ± 36.2 |
57.77 ± 41.3 |
171.5 ± 91.3* |
| 67.2 ± 41.3 |
30.9 ± 11.4 |
61.3 ± 49.2 |
39.4 ± 35.1 |
212.9 ± 191.2 |
23.83 12.4 |
| Serum creatinine (mg/dl)
Mean ± SD |
1.58 ± 1.16 |
1.61 ± 1.51 |
1.97 ± 1.86 |
| 1.6 ± 1.1 |
1.2 ± 0.7 |
1.7 ± 1.6 |
0.8 ± 0.43 |
2.3 ± 1.9 |
0.8 ± 0.4 |
| Serum potassium (mEq/L)
Mean ± SD |
4.2 ± 1.05 |
5.3 ± 1.3 |
3.9 ± 1.1** |
| 4.3 ± 0.8 |
4.2 ± 0.6 |
5.7 ± 1.4 |
2.9 ± 1.8 |
4.1 ± 0.8 |
3.4 ± 1.7 |
| Serum ALT (IU/L)
Mean ± SD |
57.8 ± 19.2 |
52.81 ± 49.8 |
93.7 ± 32.5* |
| 61.7 ± 16.23 |
32.6 ± 7.4 |
58.95 ± 8.11 |
45.45 ± 12.11 |
108.7 ± 36.1 |
39.8 ± 20.3 |
| Serum AST (IU/L)
Mean ± SD |
62.08 ± 25.9 |
42.9 ± 23.7 |
130.2 ± 45.9* |
| 66.30 ± 19.4 |
30.6 ± 9.3 |
47.14 ± 27.3 |
19.4 ± 14.2 |
156.4 ± 41.1 |
35.3 ± 27.1 |
| * P < 0.05 / ** P ≤ 0.01 |
| Number () of studied cases laboratory findings according to different digoxin concentrations (n= 217) |
| Blood urea nitrogen (mg/dl) (10-20 mg/dl) |
| No () within normal range
No () above normal range
No () > triple the normal range |
50 (56.8)
32 (36.4)
6 (6.8) |
77 (74.8)
21 (20.4)
5 (4.8) |
16 (61)
6 (23.7)
4 (15.3) |
| Serum creatinine (mg/dl) (0 .5 -1.1 mg/dl) |
| No () within normal range
No () above normal range
No () > triple the normal range |
50 (56.8)
32 (36.4)
6 (6.8) |
77 (74.8)
21 (20.4)
5 (4.8) |
16 (61)
6 (23.7)
4 (15.3) |
| Serum potassium (mEq/L) (3.5-5.5 mEq/l) |
| No () Hypokalamia (<3.5 mEq/L)
No ()within normal range
No()Hyperkalaemia(>5.5 mEq/L) |
17 (19.3)
69 (78.4)
2 (2.3) |
13 (14.7)
85 (82.5)
5 (5.6) |
5 (19.2)
19 (73.2)
2 (7.6) |
| Serum ALT (IU/L) (5-40 IU/L) |
| No () within normal range
No () above normal range
No () > triple the normal range |
72 (81.9)
11 (12.5)
5 (5.6) |
67 (65)
15 (13.5)
21 (20.5) |
16 (61.5)
6 (23.5)
4 (15) |
| Serum AST (IU/L) (5-50 IU/L) |
| No () within normal range
No () above normal range
No () > triple the normal range |
65 (73.8)
14 (16)
9 (10.2) |
67 (66)
16 (15.5)
19 (18.5) |
20 (77)
3 (11.5)
3 (11.5) |
