Groups Percentage ( No)
Subtherapeutic Therapeutic Toxic
Trough Level Peak Level Trough Level Peak Level Trough Level Peak Level
Group I (1 month) 49.5(44) 65.5 (30) 43.8 (39) 13 (6) 6.7(6) 21(10)
Group II (2-4 months) 51.8 (43) 52 (21) 42.4 (35) 28 (11) 5.8(5) 20 (8)
Group III (4 -6 months) 46.2 (40) 54.3(19) 46.2(40) 16.3 (6) 7.6(7) 29.4 (10)
Group IV (6-8 months) 38.1 (24) 46.6 (15) 50.8 (32) 34.7 (11) 11.1(7) 18.7 (6)
Group V (8-10 months) 53.5 (38) 54.2 (13) 43.7 (31) 12.5 (3) 2.8 (2) 33.3 (8)
Group VI (10-12 months) 50.8 (30 ) 56.7 (17) 47.6 (29) 2 0 (6) 1.6 (2) 23.3 (7)
Group VII (>12 months) 45.6(31) 55.6 (15) 45.6 (31) 22.2 (6) 8.8 (6) 22.2 (5)
*289 referral blood samples for both trough and peak levels–233 referral blood samples for trough level only (total referral blood samples 522).
Table 2: Total percentages of cyclosporine levels in trough-peak as per diversified therapeutic range (n=522).