| Treatment |
Mean paw volume ± SEM |
Mean ankle joint diameter ± SEM |
|
|
|
|
| |
7 DAY |
14 DAY |
21 DAY |
28 DAY |
21 DAY |
28 DAY |
| DC |
7.89 ± 0.18 |
7.93 ± 0.30 |
7.63 ± 0.25 |
6.75 ± 0.06 |
8.53 ± 0.07 |
8.49 ± 0.10 |
| STD (P) |
6.72 ± 0.21** |
6.83 ± 0.25* |
6.63 ± 0.13* |
6.23 ± 0.11* |
7.72 ± 0.22* |
7.73 ± 0.22* |
| SV1 (P) (1μg/200gm) |
7.04 ± 0.26* |
6.9 ± 0.21* |
6.64 ± 0.27* |
6.24 ± 0.13* |
7.72 ± 0.24* |
7.65 ± 0.18* |
| SV2 (P) (2μg/200gm) |
7.54 ± 0.11 |
6.91 ± 0.25* |
6.63 ± 0.13* |
6.15 ± 0.09** |
8.66 ± 0.12 |
7.67 ± 0.22* |
| STD (T) |
7.75 ± 0.08 |
8.18 ± 0.21 |
6.65 ± 0.21* |
6.27 ± 0.13* |
8.09 ± 0.18 |
7.66 ± 0.25* |
| SV1 (T) (1μg/200gm) |
7.55 ± 0.14 |
8.32 ± 0.31 |
7.74 ± 0.38 |
6.23 ± 0.13* |
8.32 ± 0.10 |
7.74 ± 0.08* |
| SV1 (T) (2μg/200gm) |
7.51 ± 0.24 |
7.05 ± 0.21 |
6.6 ± 0.18* |
5.92 ± 0.08** |
8.25 ± 0.26 |
7.741 ± 0.16* |
Values are expressed in mean ± SEM (n=6); *p<0.05, **p<0.01 vs. Disease control group, Data analysed by One-way ANOVA test followed by Dunnet’s multiple test for
comparison. Treatment of various group are as follows, DC: Disease Control, STD: Indomethacin, SV: Scorpion Venom, P: Preventive treatment, T: Therapeutic treatment. |
