Treatment Blood parameters Biochemical parameters
Hb RBC WBC SGOT SGPT
DC 9.4 ±0.4 4.6 ±0.3 13.8 ±1.0 293.9 ±11.8 182.8 ±14.0
STD (P) 12.3 ± 0.2* 6.4 ± 0.1** 14.6 ± 2.0 227 ± 29.9* 118.8 ± 10.6**
SV1   (P) (1 μg/200gm) 8.9 ±0.8 5.2 ± 0.1 2.8 ± 0.3** 228.3 ± 6.1* 97.97 ± 6.8**
SV2    (P) (2 μg/200 gm) 7.3 ±0.3 3.9 ± 0.3 2.6 ± 0.1** 216.45 ±9.9** 81.32 ± 7.0**
STD (T) 11.8 ± 0.4* 5.8 ± 0.1* 9.6 ± 1.4 219.11 ± 21.2* 78.25 ±8.7**
SV1   (T) (1 μg/200 gm) 11.85 ± 0.2* 6 ±0.1* 6.11 ±0.3** 228.01 ± 6.5* 87.75 ±4.5**
SV2    (T) (2 μg/200 gm) 12.13 ± 1.0* 6.43 ± 0.6** 6.15 ± 0.1** 230.76 ± 8.6* 99.35 ± 3.0**
Values are expressed in mean ±SEM (n=6); *p<0.05, **p<0.01 vs. Disease control group, Data analysed by One-way ANOVA test followed by Dunnet’s multiple test for comparison. Treatment of various group are as follows, DC: Disease Control, STD: Indomethacin, SV: Scorpion Venom, P: Preventive treatment, T: Therapeutic treatment.
Table 6: Effect of SV (1 and 2 μg/200 gm) on blood and biochemical parameters in FCA induced arthritis.