| Patient characteristics |
n (%) |
| Demographic data |
Patients included (hereof male) |
259 (190 or 73%) |
| Age ± SD [male/female], years |
68 ± 11[68 ± 11/68 ± 12] |
| BMI ± SD [male/female], kg/m2 |
27 ± 4 [27 ± 4/26 ± 6] |
| Risk factors for cardiovascular disease |
Hypertension |
170 (66) |
| Hypercholesterolemia |
170 (66) |
| Diabetes mellitus, on insulin |
35 (14) |
| Smoker/ex-smoker |
122 (47)/21 (8) |
| Extracardiacarteriopathy |
18 (7) |
| Previous stroke |
26 (10) |
| Alcohol overuse |
48 (19) |
| Clinical features |
Left ventricular ejection fraction |
>50 |
152 (59) |
| 31-50 |
62 (24) |
| 21-30 |
18 (7) |
| <21 |
10 (4) |
| Not reported |
17 (7) |
| Glomerular filtration rate ml/min/1.73 m2 |
>85 |
72 (28) |
| 50-85 |
132 (51) |
| <50 |
52 (20) |
| Not reported |
3 (1) |
| New York Heart Association class |
1 |
81 (31) |
| 2 |
86 (33) |
| 3 |
74 (29) |
| 4 |
8 (3) |
| Not reported |
10 (4) |
| CCS class 4* |
13 (5) |
| Recent myocardial infarction |
65 (25) |
| Chronic obstructive pulmonary disease |
40 (15) |
| Poor mobility |
16 (6) |
| Surgical conditions | Critical preoperative state | 9 (3) |
| Elective/urgent/emergency | 207/43/9 |
| Number of procedures 1/2/3 | 190/73/6 |
| Active endocarditis | 4 (2) |
| Postoperative findings | O2 saturation ± SD | 97± 7 |
| Potassium ± SD | 4.2± 0.5 |
| Number of QT prolonging drugs administered | Average | 1.37 |
| 1 | 117 (45) |
| 2 | 30 (12) |
| 3 | 12 (5) |
| 4 | 3 (1) |
| QTc duration ± SD, ms | All [male/female] | 462 ± 43 [458 ± 43/472 ± 41] |
| QTc 481-500 ms (%) | All [male/female] | 22 (9) [15(8)/7(10)] |
| QTc>500 ms (%) | All [male/female] | 47(18) [30(16)/17(25)] |
*CCS class = Canadian cardiovascular society angina classification. Class 4 is angina at any level of exertion including rest.